Telaprevir Cheap Ultimate Module Challenge increas the number of patient who drop out of the trial becaus of side effects: from 3.6% in the control group receiv onli standard therapi to 6.9% in those who took telaprevir for 12 week and to 7.7% of those who took telaprevir for eight weeks.
most patient take a 12-week cours of telaprevir combin therapi were abl to shorten the total length of their gruel treatment from 48 week to 24 weeksMoreover..
the drug must be given in combin with other antivir treatments,Becaus hepat C viru HCV rapidli becom resist to telaprevir. and these treatment ar continu for week after complet of telaprevir therapy.
and the hardest to cure. Without telaprevir,A l of the patient in the clinic trial were infect with HCV genotyp 1 -- the most common U.S. strain. less than half of patient with genotyp 1 HCV achiev a cure.
"cure" is a rel term. Treatment doe not necessarili erad the viru from the body. Success treatment result in "sustain viral respons SVR " or "viral cure,In the world of hepat C treatment." mean that treatment ha brought the viru to undetect levels. Usually, the immun system is abl to keep ani remain HCV under control after a viral cure.
their HCV level onc again becam detect dure post-treat follow-upA bout 9% of telaprevir-tr patient who achiev SVR relaps -- that is..
Test Telaprevir' Effects
two group receiv either eight- or 12-week cours of the telaprevir/interferon/ribavirin combination,In the study. follow by 12 or 36 more week of treatment with interferon/ribavirin. Those whose HCV becam undetect at week 4 and 12 got the shorter treatment course. A third group of patient got 48 week of standard interferon/ribavirin treatment.
increas the risk of anemia,Standard interferon/ribavirin usual caus flu-lik side effects. Adding telaprevir doesn't make thi easier. rash, itching, and nausea.
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